The TGFBR1 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to ALK5, and TGFBR1. This antibody recognizes Human, Mouse, and Rat antigen. The TGFBR1 Antibody has been validated for the following applications: Immunohistochemistry.
Description
The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene